A paper proposes a notion of the Energy Resistance Principle.

    • Energy Resistance is what allows transformation.
      • Without resistance, no work can be done.
    • ER is required to sustain life, but too much of it causes stress to the body.
    • Health is not "not being sick" but "keeping in the optimal zone of ER"
      • The GDF15 biomarker shows up for excess resistance.