Take risks you can afford to lose.

That is, that won't kill you.

People with existing resources are less likely to be killed, all else equal, by the same risk.

They can absorb more downside without it bankrupting them.

A structural advantage.

Risk has upside, but also downside.

A downside that won't kill you caps the downside, leaving the uncapped upside.

Capped downside, uncapped upside.

The more the asymmetry, the more you should just do it, get as many spins of the roulette wheel as possible.